Health Sciences

Quinazolinones as novel antitumor agents

The long struggle to combat and definitively eradicate the various forms of cancer that affect millions of patients worldwide is constantly being enriched with new therapeutic tools. In this challenge, many substances extracted from plants are gaining much attention, which, compared to traditional synthetic chemotherapeutics, have the advantage of a lower incidence of side effects, with the same antitumor efficacy.

Health risk factors among pregnant women in the maman mboualé neighborhood in talangaï brazzaville (Congo)

This study The aim of this article is to determine the health risk factors favoring the contraction of infections and the loss of pregnancies among pregnant women coming for consultations at public or private health centers in the Maman Mboualé district. The survey took place from June 03 to October 17, 2023. We used data from the reports of the various health centers surveyed and a questionnaire survey of 46 women living in Talangaï.

Sulforaphane: a powerful bioactive compound with chemopreventive properties and remarkable therapeutic benefits

Cancer is a multifactorial disease, therefore it is difficult to identify the specific agents responsible for its progression and development, but lifestyle and nutrition have been shown to play an important role. Several natural compounds, especially plant extracts, are demonstrating efficacy in the development of new cancer therapies, among these compounds sulforaphane is the most studied. But one of the main challenges with sulforaphane treatment is its low solubility and oral bioavailability. Several carriers are being studied to overcome these difficulties.

Visual insights into gastric and hepatic mucormycosis: A pictorial overview

We report a case of a 51-year-old male with controlled hypertension and recent severe COVID-19 infection treated with high-dose steroids, Bevacizumab, and Remdesvir, presenting with black tarry stools, upper abdominal pain, and paleness, with laboratory findings showing severe anemia (hemoglobin 5.6 g/dL) and liver lesions, upper gastrointestinal endoscopy revealed a large excavating ulcer from the fundus to the antrum, aspirate culture confirmed Mucor spp., leading to a diagnosis of gastric mucormycosis, treated with intravenous liposomal amphotericin B followed by posaconazole, and a cons

Uncovering herbal beauty remedies: the green secret

Green Secret: Unveiling Herbal Beauty Remedies" digs into the potential of herbal cosmetics in today's beauty landscape. Rooted in ancient traditions yet adapted for contemporary needs herbal beauty remedies offer sustainable, eco-friendly alternatives to synthetic products. It examines the health benefits of plant-based ingredients, emphasizing efficacy, safety, and environmental advantages. The study also investigates the science behind commonly used herbs. It delves into their active components and their uses in skin care.

Prevalencia de segundos conductos mesiovestibulares en primeros molares superiores, evaluados mediante tomografía axial computarizada

Antecedentes: Una de las fuentes de infección persistente en los primeros molares superiores, es la dificultad de localizar y tratar todo el sistema radicular durante una endodoncia primaria. Cuando el conducto MV2 no se puede tratar adecuadamente, puede contribuir a que el paciente continúe con el dolor e incluso representar una causa de fracaso del primer tratamiento endodóntico.

E-portfolio and mooc for teacher training: techno pedagogical approach: a theoretical and methodological framework

The integration of digital technologies, particularly MOOCs and e-portfolios, has transformed teacher professional development. MOOCs offer scalable learning opportunities, giving teachers access to diverse resources, while e-portfolios provide personalized spaces for reflection and tracking progress. Combining these tools in teacher training creates a flexible, learner-centered approach that enhances accessibility and effectiveness.

Ectopia cordis with fetal hydrops and severe oligohydramnios: A case report

Ectopia cordis is a rare congenital anomaly where the heart is partially or completely extruded from the thorax. It can occur with other associated defects, especially as part of the Pentalogy of Cantrell (a collection of 5 congenital midline birth anomalies; involving the sternum, heart, pericardium, diaphragm, and abdominal wall).

Anesthetic management in simultaneous surgery: cesarean section and meningioma resection

Managing the simultaneous performance of a cesarean section and intracranial meningioma resection in pregnant patients presents a significant anesthetic challenge. This case report describes a 34-year-old woman at 27 weeks of pregnancy diagnosed with a left pontocerebellar angle meningioma. The patient experienced acute neurological deterioration, necessitating urgent surgical intervention comprising a cesarean section and tumor resection in a single operative session.

Sacrococcygeal teratoma in a limited-resource setting: A case report

Introduction: Sacrococcygeal teratoma (SCT) occurs commonly in neonates and infants and poses significant obstetric and fetal challenges, especially in resource-strained settings. SCT affects 1 in every 35,000–40,000 live births. Prompt diagnosis and effective management of SCT improve obstetric and neonatal outcomes. Case presentation: A 25-year-old gravida 2 para 1+0 at 27 weeks gestation was admitted to the hospital with complaints of intermittent lower abdominal pain and reduced fetal movements.