Background: Obesity and cardiovascular fitness are interrelated, with lifestyle management playing a crucial role in improving cardiopulmonary function. This study examines the correlation between stress test results and obesity, emphasizing lifestyle interventions. Methods: A retrospective, multi-centric, observational study was conducted from January 2024 to September 2024. A total of 24 patients(Males: 87.5%, Females: 12.5%) aged30-75 years diagnosed with IHD (positive stress test) with Obesity (BMI) >25regardless of underlying comorbidities were included in this study. The primary endpoint was improvement in Vo2max and BMI from baseline to the 90-day follow-up. Secondary endpoints were improvement in weight, ABG (Abdominal girth), systolic blood pressure (SBP), diastolic blood pressure (DBP), and heart rate (HR) and reduction in dependency on allopathic medication from baseline to the 90-day follow-up. Results: Mean age of the study population was 58.00±10.24 years. The primary endpoint of Vo2maximproved from 12.71±3.20 to 17.36±6.96, p=0.00 and BMI 29.00±3.46 to 27.92±3.24 at the 90-day follow-up. Secondary endpoints of Met value (day 1: 3.61±0.89and day 90: 4.96±1.99, p=0.02), weight (day 1: 76.97±10.08kgand day 90: 73.73±10.19kg, p=0.00), ABG (day 1: 104.04±9.24 and day 90: 99.96±8.59, p=0.00), and SBP (day 1: 136.83±21.16 and day 90: 131.67±16.76; p=0.04) , DBP (day 1: 79.46±12.36 and day 90: 76.63±12.56; p=0.04) also improved at the 90-day follow-up. Reduction in allopathic medication doses was also observed. Conclusions: The 90-day intervention had a positive impact on various health parameters, including improvements in VO2max and BMI, highlighting its effectiveness in addressing obesity.
