February 2025

In this essay, I develop the concept of background and foreground. This may alternatively be understood as the post structural demarcation of presence and absence. Based on this, I argue initially theoretically and then as applied to apparent grand narratives: mathematics and science; art; philosophy; politics; psychology and briefly religion. arguing that no grand narrative (ultimate paradigm) is forthcoming and what appears to be a foreground may recede into the background depending on the focus. I conclude that perhaps mysticism or some form thereof is the only solution for both arguing for the concept of a grand narrative and for access to such an “entity”, the cause.

Over the years, the woman'srole in society has stood out in the direction of upward progression. These highlights boosted his social, family and cultural position. On the other hand, the current situation presents spouses with ethical and moral challenges that interfere with their coexistence experiences and personality traits. This work aims to verify the implications of marital coexistence on affective changes, ethical principles and personality traits in a group of women in long-term relationships. The study was carried out from February to March 2023 on women in a relationship of 5 years or more, by filling out a questionnaire that assessed affectivity, ethical principles and personality traits taking into account the experiences of coexistence conjugal. Data were collected through conventional sampling and analyzed using SPSS statistical software. 110 womens from different social strata participated in this study, aged between 38 and 42, the majority of whom had been together for more than 20 years. The results demonstrate that variables such as affectivity, ethical principles and personality traits are among the factors with the greatest weight in the Component Matrix. It was also found that there is a statistically significant association between affection, ethical principles and personality traits of the spouses. Fidelity behavior is correlated with marital satisfaction. Changes in personality patterns are related to emotional expression and ethical principles. Most of the women interviewed state that in long-term relationships, ethical principles and affection can produce significant changes in the spouses' personality traits and increase marital satisfaction.

Modern data processing has brought data streaming architecture to become a vital element that processes data in real-time, which the traditional batch processing approach cannot. With the amount of data that businesses, especially businesses in the healthcare sector, produce, real time processing and analysis of it is necessary. In this work, we investigate the advantages and disadvantages of data streaming architecture under consideration of healthcare applications. This study focuses on the implementation and effectiveness of data streaming architecture in healthcare settings as the major goal of the work. More specifically, its objective is to understand how the use of data processing could contribute to patient care to save costs and improve operational efficiency. It then hypothesizes that real-time insight, cost of use, and scalability make data streaming architecture so superior to traditional batch processing. Using case studies in two areas of healthcare, real time monitoring of patient vital signs and predictive maintenance of medical equipment and real time mode of wearable physiologic data from chronic disease cases, this study investigates the application of a data streaming architecture. The study design is a qualitative analysis of the challenges the planners faced during implementations, lessons learned, and outcomes realized. Quantitative methods are applied to the quantification of operational efficiency cost savings improvements, and patient outcomes. The study shows that data streaming architecture provides a significant advantage in the case of healthcare applications. Take as an example, it could enable nearly real-time monitoring of patient vital signs, enabling prompt medical intervention and resulting in a great improvement in patient outcomes. Medical equipment was predicted to be maintained, which led to cost savings and reduced the downtimes of the equipment. Wearable device data analysis in real time is conducted to come up with personalized patient recommendations that improve the management of the chronic disease. Statistical data presented the support of these findings in the improvements in operational efficiency and cost reductions. The study concludes that the data streaming architecture technology has the potential to transform healthcare in a real time, cost-effective and scalable manner. The results presented here have relevance to both enhanced patient care, operational cost savings, and increased efficiency in the case studies. Finally, future research should aim at addressing these unresolved challenges in privacy, accuracy, and scalability so that the power of the data streaming architecture could be fully utilized in other data-intensive industries including healthcare.

The purpose of this study was to determine the mediating effect of science learning environment on the relationship between student academic motivation and self-efficacy of senior high school student of Baganga North District Division of Davao Oriental, Region XI, Philippines. The study utilized a quantitative, non-experimental design via correlational technique and mediation analysis.Futhermore,204 senior high students respondents were survey using universal sampling an adapted 5 point likert scale survey questionnaires. Weighted, mean, Pearson r, and multiple regression were used as statistical tools. Moreover, all of the three variables obtained a high level and revealed a significant relationship between student academic motivation and self-efficacy, there was a significant relationship between science learning environment and student academic motivation and a significant relationship between science academic motivation and self-efficacy of senior high school students, three variables. Furthermore, science learning environment has a partial mediating effect on the relationship between student academic motivation and self-efficacy of students in science. This means that the science learning environment influences the strength of the relationship between the student academic motivation and self-efficacy.

Caffeine citrate has been implemented to some extent worldwide withinneonatal units for preterm baby’s obstructive sleep apnea management. Almost, preterm babies are prone to obstructive sleep apnea, plus elevated death risk or even disabilities. Up to date, caffeine citrate is addressed for preterm babies` apnea targeting to reduce bronchopulmonary dysplasia incidence, as well neurodevelopmental disability at 18-21 months. Caffeine citrate is recognized to havelong-term safety, particularlyrelating to motor, behavioral, and intelligence skills. Prenatal caffeine predisposes to intrauterine growth restriction and small growth for gestational age at birth. Caffeine citratehas a cost-effective pharmacotherapy benefit, in terms of safety, and efficacy for preterm babies’ apnea, and modulating rates of bronchopulmonary dysplasia within neonatal intensive care units.

Ecological ethics serves as a tool to raise human awareness about the real meaning of preserving and conserving nature. This article is part of environmental concern and the desire to bring proposals for solutions to change the behavior and habits of Farmers regarding the use of natural resources in Cabinda. In recent years, the Province has been recording a wave of deforestation resulting from the process of removing or cutting down sections of virgin forest for economic purposes. So, it was from this perspective that the research was carried out among women who practice shifting cultivation in rural areas, to understand whether they really know about the irreversible environmental damage caused by this agricultural production system. However, it was found that they lack any information and knowledge regarding the subject. This led to the following question: what are the factors behind the lack of information and knowledge regarding the risks of shifting cultivation practiced by Women in Rural Areas? And How can ecological ethics influence the acquisition of information and knowledge about these risks? The answers to these questions were associated with factors such as level of education, lack of time to follow the newspaper and lack of public actions or policies aimed at rural education. Materials and methods: the questionnaire was applied to a sample of 126 Peasant Women, whose opinions were processed in the SPSS software, allowing statistical processing of the data. Results: of the 126 respondents, 39.95% are between 48 and 58 years old, around 63.49% are married, 68.25% have primary education, 19.05% have secondary education and only 12.70% have high school education, 99.99% stated that they cut down and burn vegetables and use the ashes as nutrients for the soil, and 99.99% stated that they do not watch the news to get information about the consequences and dangers of this practice, 98.41 % have a level of environmental education considered terrible. Conclusion: after the study carried out, it is concluded that it is necessary to promote actions that make Women aware of the importance of conserving the environment, starting with the construction of field schools and holding an environmental forum in rural areas.

Background: It is essential to investigate the effectiveness of antibiotics in the present-day scenario, especially because of the increasing threat of antimicrobial resistance. Cefuroxime, a second-generation cephalosporin, has a broad spectrum of antimicrobial activity. However, there is a dearth of data on the current susceptibility of pathogenic bacteria to cefuroxime or its combinations. Objective: This study aimed to evaluate the in vitro susceptibility of clinical isolates to cefuroxime in combination with β-lactamase inhibitor, clavulanic acid, as there are no clinical breakpoints for interpretation of antimicrobial susceptibility. Methods: Bacterial isolates were cultured from non-repetitive clinical samples from January to February 2024 at a single center in India. Minimum inhibitory concentration (MIC) of cefuroxime + clavulanic acid was evaluated using Epsilometer test (E-test). The MIC values thus obtained were used to assess susceptibility of isolates. Results: Among 100 clinical isolates tested, 78% were gram negative and 22% were gram positive. Escherichia coli was the most prevalent pathogen (38%), followed by Klebsiella pneumoniae (24%) and Staphylococcus aureus (16%). Since breakpoints for cefuroxime + clavulanic acid are not available, the corresponding values for cefuroxime provided in EUCAST and/or CLSI were used to deduce conclusions about susceptibility. Accordingly, susceptibility/intermediate susceptibility to cefuroxime + clavulanic acid was displayed by 68.42% of E. coli, 41.67% of K. pneumoniae, and 12.50% of S. aureus isolates. Other less-prevalent bacteria such as Enterobacter cloacae, Serratia marcescens, Proteus mirabilis, Citrobacter koseri, Salmonella enterica, Proteus vulgaris, and Pantoea spp. were also found to be susceptible/intermediately susceptible to cefuroxime + clavulanic acid. Conclusions: A fixed-dose combination (FDC) of cefuroxime and clavulanic acid was effective against pathogens like E. coli, K. pneumoniae, S. aureus, and others. Given these broad spectra of activity, this FDC appear well-suited for use in the treatment of a variety of healthcare-associated infections, such as pneumonia, surgical sepsis and/or bacteremia, UTIs, etc.

The long struggle to combat and definitively eradicate the various forms of cancer that affect millions of patients worldwide is constantly being enriched with new therapeutic tools. In this challenge, many substances extracted from plants are gaining much attention, which, compared to traditional synthetic chemotherapeutics, have the advantage of a lower incidence of side effects, with the same antitumor efficacy. Among the substances of plant origin there are the Quinazolinones, from which many chemical derivatives have been synthesized, which have demonstrated a broad spectrum of therapeutic efficacy. In this work, we will review the therapeutic properties of the main Quinazolinone derivatives, and their supposed mechanism of action. They are very promising substances with positive developments in the fight against neoplastic pathology.

The Senate President, Godswill Akpabio, of the ruling All Progressives Congress (APC) while addressing delegates of the Niger Delta Development Commission (NDDC) in Rivers State said that those who wanted to protest against bad governance in the country could go ahead while he and his colleagues would be eating. This video went viral and caused outrage among Nigerians. This research investigates audience perception of Senator Akpabio’s “Let them protest while we eat” comment which went viral on social media and how this statement influenced people’s perception of the current Administration in Nigeria. The Survey research method was used to study 384 respondents derived using the Cozby’s table. The study was anchored on the Perception theory. The objectives of study are to ascertain the frequency of exposure to “Let them protest while we eat” comment on Facebook by COOU students, to ascertain their perception of the comment, to ascertain whether respondents reposted the comment to their friends and to ascertain whether exposure to the comment on Facebook influenced them to support the End Bad Governance protest in the country. The result showed that respondents were very highly exposed to Akpabio’s “Let them protest while we eat” comment on Facebook and they had negative perception of the comment as they saw it as a mockery of the plight of Nigerians and insensitivity to the suffering of people in the country. The study recommended among others that Senator Akpabio and other elected officials should use the social media to promptly correct wrong impressions and apologize for insensitive comments as damage control in order not to incite the public into more protests. It is also recommended that Public Relations strategies should be effectively utilized by the current Administration so as to calm the nerves of the suffering Nigerians.