In-vitro interaction of b-crystallin on serum amyloid a and serum amyloid a fibrils with bc3h1 cells
The BC3H1 smooth muscle cells of mice brain, BC3H1 is a permanent cell line derived from a mouse brain tumor. When these cells become quiescent, they express the muscle form of creatine phosphokinase, myokinase, the nicotinic acetylcholine receptor, as well as smooth muscle a-actin, all indicative of a muscle phenotype. This is important in relation to the activity of membrane proteins, because losing the activity of such systems will ultimately lead to malfunction or death of the cell.