This study examined the dissemination of health information to stakeholders in Tanzania. The study aimed at determining the channels used to disseminate health information and the challenges hindering the dissemination of health information in Tanzania with specific reference to Muhimbili University of Health and Allied Sciences (MUHAS) library. This study used the Mixed Approach. Convenience sampling was used to draw a sample of thirty one library professionals and teaching staff at MUHAS Library. Data were collected through questionnaires where by both open ended questions and closed questions were asked. Statistical Package for social sciences was used to analyse the descriptive statistics and the findings were presented in contingency tables and figures. The findings showed that the major channels for disseminating health information include: brochures, research reports, journals, news papers, exhibitions, press conferences, social media, radio, short messaging services, drama, seminars, and community based organizations. Other channels include: primary school pupils, religious leaders, website, health service providers, and flayers. Further it was revealed that challenges hindering dissemination of health information to stakeholders include: financial constraints, unreliable electricity in some rural areas, researchers’ poor motivation and inadequate skills in repackaging information sources, poor reading culture, and language problem. The study concludes that the government through the ministry of health, community development, gender, elderly, and children (MoHCDGEC) should address all the identified challenges hindering the dissemination of health information to stakeholders at MUHAS, Tanzania. The study therefore, recommends that measures such as allocation of enough budget and provision of training in repackaging to researchers could enhance the dissemination of health information in the Country.