Introduction: The STOP-Bang questionnaire has been useful to identify patients with high risk of oxygen desaturation, among others postoperative complications. Objective: Determine the association of oxygen desaturation with the high STOP-Bang questionnaire applied in preanaesthetic consultation. Materials and methods: Observational, prospective, longitudinaldesign. It was performed in the Navy Medical Center. The study included patients over 18 years old divided into two groups under general anesthesia: the STOP-Bang score < 3 and ≥3. The patients were assessed with the STOP-Bang questionnaire, sensitivity for moderate 93%. Analyzed through descriptive statistic-study and Xi2, significance p<0.05. And statistic package SPSSv24.0. Results: A sample of 121 patients were programmed for surgery under general anesthesia, The STOP-Bang scores high 85 and low 36. Patients over 50 years old in 49 (58%) high STOP-Bang score; atrial fibrillation 17 (17.6%) high STOP-Bang and 0% low STOP-Bang scores. Hypertensive patients of 52 (61%) high STOP-Bang and 5 (14%) low scores, p<0.000. Oxygen desaturation in 18 (21%) STOP-Bang high and, 1 (3%) low scores, p<0.012 OR 9.4 (IC 95% 1.2-73.3). Conclusions: Higher scores of STOP-Bang were associated to oxygen desaturation and cardiovascular disease risk.