Successful Outcome Of Pregnancy In A Case Of Recurrent Pregnancy Loss With Protein S Deficiency

We are presenting a case of fourth Gravida with history of previous three spontaneous late first trimester miscarriages. She was diagnosed with protein S Deficiency in non-pregnant state after screening for thrombophilia. The prophylactic therapy with low molecular weight heparin along with Aspirin was introduced from the 6th week of gestation after fetal cardiac activity was appreciated on ultrasound & continued for whole of the gestation. She underwent planned caesarean section at 38 weeks of gestation resulting in the delivery of a healthy male new born of 2.6 kg body weight. Prophylactic Low Molecular Weight Heparin was continued for 6 weeks post partum to avoid thrombo-embolic complications.