A single blind, randomized, placebo controlled, multicentric study comparing the efficacy & safety of rheumax capsules in the patients with mild to modarate rheumatoid arthritis

Author: 
Dr. Chhapekar Shrirang, Dr. Deshpande Sarang, Dr. Khandizod Shivapal G., Dr. Padvi D. M., Dr. Bhadalikar Deodatta, S. and Dr. Malekar Shailesh

Rheumatoid arthritis (RA) is a common chronic inflammatory disease affecting over 4,00,00,000 people in the world. RA is associated with significant morbidity including pain and disability. It does not just affect synovial joints but is a systemic disease affecting other organs. It is also associated with increased mortality. Currently used regimens for RA i.e analgesics, steroidal and non-steroidal therapies and DMARD’s (diseases modifying antirheumatic drugs) are yet to get sure significance to improve lifestyle of a patients and safety concern, resistance and tolerance to the therapies are other serious concern towards treatment of RA with this conventional therapies. Herbal treatments provide comparatively safe and multidimensional approach towards the disease modifying index of RA in a holistic manner. Rheumax capsule is a blend of extracts presented in a standardized and advanced dosages form of pellets in a capsule form, provides safe, palatable and efficacious approach. Current multicentric, placebo control study on 132 patients, with proper GCP and ethical concern in adose of 2 capsules BID proves that Rheumax capsule significantly improves quality of life of a patient significantly after 4th week of treatment and highly significantly after 8th, 10th and 12th week of treatment as compared with placebo in VAS, DAS and RADAI with no adverse effects on biochemical parameters. also significant results in symptoms score of pain, stiffness, tenderness and swelling indicates that Rheumax capsule is an effective remedy for the patients suffering from the symptoms of rheumatoid arthritis.

Paper No: 
1959