Role of statins in developing diabetes mellitus

Author: 
Prof. (Dr.) Keerthi G S Nair, Megha J. R., Dr. Amal A., and Prof. Dr. Shaiju S. Dharan

Background: Diabetes is thought to carry the same risk as coronary heart disease.The higher chance of cardiac mortality and incident coronary heart disease (CHD) development are especially concerning in case of diabetes. The usefulness of statins in primary and secondary prevention of cardiovascular disease (CVD), including among people with type 2 diabetes, is well established. Across all cardiovascular risk groups, there is compelling evidence that statins reduce major vascular events. While statin therapy lowers the risk of cardiovascular disease, there is debate regarding its link to the onset of diabetes. Trials of statin therapy have provided conflicting results regarding statin use and type 2 diabetes (T2DM). Methods: Previously published articles relating to the topic Statins and Diabetes mellitus have been collected and reviewed. Observations: Using statins is linked to a higher risk of type 2 diabetes. Using statins is linked to a higher risk of type 2 diabetes (T2DM), which rises with continued usage and higher baseline BMI values. The ongoing researches regarding Statins and Diabetes development will certainly create an alarming sign among the physicians.

Paper No: 
5454