Purpura Fulminans (PF) is a life-threatening thrombotic disorder of acute onset which is characterized by cutaneous hemorrhage due to severe bacterial, viral infections or may be idiopathic. Disseminated intravascular coagulation (DIC), antiphospholipid antibodies and acquired or congenital C and S protein deficiency play a role in its pathogenesis. Here we report two cases of purpura fulminans in infants due to viral infections (dengue hemorrhagic fever and disseminated varicella) complicated by DIC.
Paper No:
361
