Malignant hyperthermia (MH) is a severe and sudden increase in metabolism, the common clinical manifestations are: High central temperature, increase in ETCO2, hyperkalemia, acidosis, muscle rigidity and cardiovascular instability, after exposure to certain anesthetic drugs. Malignant hyperthermia occurs in persons who have a genetic alteration in the sarcoplasmic reticulum of striated.
Paper No:
2624