The emergence of Logistics Industry 5.0 represents a paradigm shift in the logistics sector, focusing on seamless collaboration between human expertise and cutting-edge technology. This paper explores the transition from traditional logistics models to Logistics 5.0 within the Malaysian landscape, emphasising the critical role of human-machine synergy in shaping workforce management. Through a comprehensive literature review and an in-depth analysis of three Malaysian case studies, this study examines the practical implementation, advantages, and benefits of integrating Logistics 5.0 principles. Findings indicate that while automation and artificial intelligence drive efficiency and productivity, human intuition, adaptability, and strategic oversight remain indispensable. The paper concludes with actionable recommendations to enhance human-machine collaboration, ensuring that Malaysia's logistics industry remains resilient, innovative, and future-ready in an era of rapid technological evolution.