Aim: This study was done to evaluate the efficacy of the post-operative antibiotic therapy in reducing post-operative indiscriminate use of antibiotics and to evaluate whether it is important to give antibiotics regime in asymptomatic tooth extraction. Methods and Materials: The sample of 60 patients were selected in the Department of Oral and Maxillofacial surgery at Swargiya Dadasaheb Kalmegh Smruti Dental College and Hospital. Group A being the study group were NSAIDs given and antibiotics regime was excluded and Group B being the control group were antibiotics regime was given. The patients were followed up for 2nd, 4th, 7th, 10th, 14th day of extraction post-operatively. The assessment of pain, healing and swelling of extraction wound were evaluated. Statistical Analysis: The results were evaluated by comparing the data between two groups. It was statistically evaluated using EPI Info software version 6 using Unpaired ’t’ test and Chi square test. Results: Pain was statistically significant in group A than group B with P value<0.001 on 2nd, 4th and 10th day. On 14th day there was no significant difference. Swelling was assessed intraoral as well as extra orally showing statistically significant in group B with Pvalue <0.005. Healing was assessed using Laundry, Turnbell and Howley index shows statistically significant in group A than group B with Pvalue <0.005. Conclusion: We conclude that antibiotic regime is not necessarily required in post extraction of asymptomatic tooth.
