Background: Pregnancy has being found to be associated with changes in serum uric acid, serum creatinine and serum urea and this differs with each trimester. Material & Methods: This cross-sectional study was conducted at Shendi locality. The patients underwent a clinical assessment, which included history (a questionnaire) and clinical examination. 160 women were divided into four group’s non pregnant, 1st, 2nd and 3rd trimester of pregnancy respectively. The age limits was 12 to 40 years. Results: The mean of serum uric acid, urea andcreatinine showed lower values in pregnant groups ofpregnancy than the non-pregnant (control group). While the mean value of serum uric acid1sttrimester ofpregnancy show a significant decrease compared to thenon-pregnant (control group). There was a significant difference in serum uric acid and creatinine betweenthe 1st and 3rd trimester which were higher in the 3rd trimester than the 1st trimester ofpregnancy, but no significant difference in serum urea between the 1st and 3rd trimester.Comparison between numbers of pregnancy and the serum urea, uric acid and creatinineconcentration are not significant. Conclusion: The mean of serum uric acid, urea andcreatinine showed lower values in pregnant groups than the non-pregnant (control group).
