Victims of arthropod-borne diseases may be unaware of the source or circumstances of infection. Symptoms are often vague, initially, and characteristic lesions at the bite site or rashes may be lacking. This review aims to enhance the awareness and recognition of currently relevant diseases borne by hemophagous ectoparasitical arthropods, namely, fleas (endemic typhus and flea-borne spotted fever, plague, cat-scratch disease), human body lice (epidemic typhus, trench fever, louse-borne relapsing fever), and soft ticks (tick-borne relapsing fever). Each disease is described according to five criteria, which are important in disease identification and preventive awareness: Pathogen, vector, incubation period, symptoms, and region.