Post-COVID conditions are wide range of new, returning or ongoing health problems that people experience after being infected with the virus during epidemic [COVID-19]. Most people with COVID-19 presented with different health problems noted in different opd clinics. Anyone who as infected can experience post-COVID conditions. Most people with post-COVID conditions experience symptoms days after first learning they had COVID-19, but some people who later experienced post-COVID conditions didnot know when they got infected. People with post-COVID conditions can have wide range of symptoms that can last weeks, months or even years after infection. Sometimes the symptoms can even go away or come back. In Charaka Samhita Vimana sthana; Janapadhodwamasa adhyaya, mentioned about treating the condition with Panchakarma followed by Rasayana. Here in this case report, Mridu Kayashodhana followed by Rasayana is taken to see the changes in post-covid subjects. A 61year old female subject suffers from Breathlessness, depends on oxygen mask since 6months after discharge from the hospital due to COVID-19 followed by sever fatigue, cough, sleep disturbance, anorexia etc. Treated subject with only Bharangi Guda (Naimittika Rasayana) for 30 days as disease management and rejuvenative therapy to see the variations.