Acute myeloid leukemia (AML) is a type of blood cancer which starts in the bone marrow. In AML, bone marrow cells do not mature. The immature cell are called blast cells, keep building up. This type of leukemia can spread quickly to the blood and to other parts of the body such as Lymph nodes, Liver, Spleen, Brain and spinal cord. In the present case study , a patient of age 23 years of acute leukaemia who was advised for bone marrow transplantation by allopathic hospital, came to take Ayurvedic consultation. The patient was treated with the concept of rakt dusti janya vyadhi. Because the rakt is similar with pitta so the ayurvedic formulation which works on balance the pitta will also work in making the rakt in equilibrium. Therfore assuming the cause of leukemia as pitta dusti , the total line of treatment was planned which can corrects the pitta and inturns rakt. Also some medicines which works on liver as it has important role in formation of blood cells, are also incorporated in the line of treatment. After a treatment of two months, the patient represented with drastic changes in signs and symptoms, with simultaneous improvement in his blood investigations too. The patient is also advised to follow pathya apathya as mentioned.